The ZIKAapp study was a one year pilot study carried out in Jamaica to monitor arbovirus symptoms in pregnant women and to develop methods for investigating outcomes of maternal ZIKV infection. ZIKApp demonstrated its feasibility and acceptability among 173 community-based pregnant women, with good participant retention (91%) and adherence to daily symptom diary completion up to delivery. An evidence synthesis using Bayesian Latent Class models to estimate the risk of vertical transmission of ZIKV by trimester of maternal infection using published data reported, estimated average risks of transmission in the 1st, 2nd and 3rd trimesters to be 46%, 28% and 25%.
