Uncategorized Archives - Zika

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An observational clinical case of Zika virus-associated neurological disease is associated with primary IgG response and enhanced TNF levels

By Delatorre E, Miranda M, et al. Descriptive clinical data help to reveal factors that may provoke Zika virus (ZIKV) neuropathology. The case of a 24-year-old female with a ZIKV-associated severe acute neurological disorder was studied. The levels of ZIKV in the cerebrospinal fluid (CSF) were 50 times higher than the levels in other compartments. An acute… Read More &raquo

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The spectrum of neurological disease associated with Zika and chikungunya viruses in adults in Rio de Janeiro, Brazil: A case series

By Mehta R, Soares CN, Medialdea-Carrera R, et al. During 2015-16 Brazil experienced the largest epidemic of Zika virus ever reported. This arthropod-borne virus (arbovirus) has been linked to Guillain-Barré syndrome (GBS) in adults but other neurological associations are uncertain. Chikungunya virus has caused outbreaks in Brazil since 2014 but associated neurological disease has rarely been reported here. We… Read More &raquo

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Vertical transmission of positive-sense single-stranded RNA viruses in plants as a model for arboviral induced teratogenesis

By Barr KL. Teratogenic viruses have increased public health importance with the emergence of Zika virus and a recent decline in rubella virus vaccination. Of the seven viruses known to cause birth defects in humans, three are mosquito-borne pathogens. Ethical oversight, compliance, rising costs, and the need for specialized training slow the pace of study of… Read More &raquo

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Study on the persistence of Zika virus (ZIKV) in body fluids of patients with ZIKV infection in Brazil

By Calvet GA, Kara EO, Giozza SP, et al. Zika virus (ZIKV) has been identified in several body fluids of infected individuals. In most cases, it remained detected in blood from few days to 1 week after the onset of symptoms, and can persist longer in urine and in semen. ZIKV infection can have dramatic consequences such as microcephaly… Read More &raquo

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