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Islands as Hotspots for Emerging Mosquito-Borne Viruses: A One-Health Perspective

By Mavian C, Dulcey M, Munoz O, Salemi M, Vittor AY, Capua I.

Within the context of the One Health approach, this review highlights how the emergence of arboviruses in tropical islands is linked to the complex interplay between their unique ecological settings and to the recent changes in local and global sociodemographic patterns. The authors also advocate for greater coordination between stakeholders in developing novel prevention and mitigation approaches for an intractable problem.

Published in: Viruses. 2019; 11(1):11.

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Evidence for multiple sylvatic transmission cycles during the 2016-2017 yellow fever virus outbreak, Brazil

By Moreira-Soto A, Torres MC, Lima de Mendonça MC, et al.

Since December 2016, Brazil has experienced an unusually large outbreak of yellow fever (YF). Whether urban transmission may contribute to the extent of the outbreak is unclear. The objective of this study was to characterize YF virus (YFV) genomes and to identify spatial patterns to determine the distribution and origin of YF cases in Minas Gerais, Espírito Santo and Rio de Janeiro, the most affected Brazilian states during the current YFV outbreak.

Published in: Clin Microbiol Infect. 2018;24(9):1019.e1-1019.e4

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Zika Virus Infection and Differential Diagnosis in a Cohort of HIV-Infected Patients

By Calvet GA, Brasil P, Siqueira AM, et al.

Zika virus (ZIKV) emergence in South America revealed the lack of knowledge regarding clinical manifestations in HIV-infected individuals. We described the clinical characteristics, laboratory manifestations, differential diagnosis, and outcome of ZIKV infection in a large, single-center cohort of HIV-infected patients.

Published in: J Acquir Immune Defic Syndr. 2018 Oct 1;79(2):237-243.

Seroprevalence of Dengue, Chikungunya and Zika Viruses in an Antenatal Population in the Greater Kingston Metropolitan Region of Jamaica

By Joshua Anzinger, University Of the West Indies, Kingston – Jamaica

The poster was presented at the 2nd International Conference on Zika Virus and Aedes Related Infections in Tallinn, Estonia on June 14th – 17th 2018.

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Investigating vertical transmission of chikungunya, dengue and zika virus infection: a prospective observational cohort study of pregnant women and infants in Jamaica

By CD Christie, C Thorne, J Anzinger, H Bailey, et al.

Poster presented at the International Symposium on Zika Virus Research, held in Marseille – France, on June 4th – 6th 2018

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Symptomatic Zika Virus Infection in Infants, Children, and Adolescents Living in Puerto Rico

By Read JS, Torres-Velasquez B, Lorenzi O, et al.

This study represents the largest study to date of ZIKV infection in the pediatric population. Most children infected with ZIKV had fever, rash, and conjunctival hyperemia. The children usually presented for evaluation at fewer than 3 days after the onset of symptoms. Viral loads for ZIKV were higher in serum vs urine specimens. Median viral loads in serum specimens differed significantly according to the number of days after the onset of symptoms.

Published in: JAMA Pediatr. 2018;172(7):686-693.


Genetic evidence of Zika virus in mother’s breast milk and body fluids of a newborn with severe congenital defects

By Giovanetti M, Goes de Jesus J, Lima de Maia M, Junior JX, et al.

On the basis of the upsurge in the number of newborns with neurologic disorders in the northeast, in November 2015 the Brazilian Ministry of Health declared a public health emergency of national concern. On the basis of evidence for a potential association between microcephaly and other neurologic disorders and Zika virus (ZIKV) infection, the World Health Organization declared a public health emergency of international concern on 1 February 2016. Here we report genetic evidence of ZIKV RNA in the mother’s breast milk and in the serum and urine of a newborn with severe congenital defects.

Published in: Clin Microbiol Infect. 2018 Oct;24(10):1111-1112.

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Clinical and Laboratory Profile of Zika and Dengue Infected Patients: Lessons Learned From the Co-circulation of Dengue, Zika and Chikungunya in Brazil

By Azeredo EL, Dos Santos FB, et al.

The current triple epidemic caused by dengue, zika and chikungunya constitutes a serious health problem in Brazil. The aim of this study was to investigate acute samples (up to the 7 days of symptoms) from patients presenting acute fever syndrome suspected as arboviral infection and characterize the clinical and laboratorial profile during the co-circulation of dengue, zika and chikungunya in Campo Grande, Mato Grosso do Sul (MS), midwest region of Brazil.

Published in: PLoS Curr. 2018 Feb 15;10.

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What we know and what we don’t know about perinatal Zika virus infection: A systematic review

By Soriano-Arandes A, Rivero-Calle I, Nastouli E, et al.

Zika virus (ZIKV) infection has caused the most challenging worldwide infectious epidemic outbreak in recent months. ZIKV causes microcephaly and other congenital malformations. There is a need to perform updated systematic reviews on ZIKV infection periodically because this epidemic is bringing up new evidence with extraordinary speed.


Published in: Expert Rev Anti Infect Ther. 2018 Mar;16(3):243-254

Evidence for Mother-to-Child Transmission of Zika Virus Through Breast Milk

By Gabriela M Blohm, John A Lednicky, Marilianna Márquez, Sarah K White, Julia C Loeb, Carlos A Pacheco, David J Nolan, Taylor Paisie, Marco Salemi, Alfonso J Rodríguez-Morales, J Glenn Morris, Juliet R C Pulliam, Alberto E Paniz-Mondolfi

Zikavirus (ZIKV) is an emerging viral pathogen that continues to spread throughout different regions of the world. Herein we report a case that provides further evidence that ZIKV transmission can occur through breastfeeding by providing a detailed clinical, genomic, and virological case-based description.

Published in: Clin Infect Dis. 2018 Mar 19;66(7):1120-1121.

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