ZIKA-HOST sub-study - Zika

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ZIKA-HOST sub-study

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Overview

The ZIKA-HOST sub-study used a ZIKV vaccine and gene expression approach to explore ZIKV infection from the host perspective, utilising a host biobank of mother-child samples from Brazil and Spain to identify host genes regulated after ZIKV infection.  

Results

Very interesting findings have emerged within this study using a Zika vaccine and a gene expression approach in the preliminary analysis of host genes regulated after infection with MVA- ZIKV vaccine aiming to identify host genes regulated after infection with MVA-ZIKV in human cells and investigate the class of immune regulatory genes that are induced by this specific vaccine against ZIKV.