Overview
The ZIKA-HOST sub-study used a ZIKV vaccine and gene expression approach to explore ZIKV infection from the host perspective, utilising a host biobank of mother-child samples from Brazil and Spain to identify host genes regulated after ZIKV infection.
Results
Very interesting findings have emerged within this study using a Zika vaccine and a gene expression approach in the preliminary analysis of host genes regulated after infection with MVA- ZIKV vaccine aiming to identify host genes regulated after infection with MVA-ZIKV in human cells and investigate the class of immune regulatory genes that are induced by this specific vaccine against ZIKV.