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    Trends in Dengue – The Jamaican experience

    By Webster-Kerr K.

    Published in: Oral presentation at 3rd international Conference on Zika Virus and aedes related infections, February 13th – 16th, 2020– Washington DC, USA.

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    Overview and preliminary results of the ZIKAction vertical transmission study in Jamaica

    By Celia DC Christie

    Published in: Oral presentation at 3rd international Conference on Zika Virus and aedes related infections, February 13th – 16th, 2020– Washington DC, USA.

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    Return of the founder Chikungunya virus to its place of introduction into Brazil is revealed by genomic characterization of exanthematic disease cases

    By Pereira Gusmão Maia Z, Mota Pereira F, do Carmo Said RF, et al.

    Between June 2017 and August 2018, several municipalities located in Bahia state (Brazil) reported a large increase in the number of patients presenting with febrile illness similar to that of arboviral infections. Using a combination of portable whole genome sequencing, molecular clock and epidemiological analyses, we revealed the return of the CHIKV-ECSA genotype into Bahia.

    Published in: Emerg Microbes Infect. 2020;9(1):53-57

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    Modulated Zika virus NS1 conjugate offers advantages for accurate detection of Zika virus specific antibody in double antigen binding and Ig capture enzyme immunoassays

    By Tedder RS, Dicks S, Ijaz S, et al.

    The accurate diagnosis and seroprevalence investigations of Zika virus (ZKV) infections remain complex due to cross reactivity with other flaviviruses. Comparing DABA and G capture assays using quenched and unquenched conjugates in comparison with EuroimmunZ early in the course of PCR-confirmed infection indicated that a significant component of the apparent early anti-ZIKA antibody response is likely to be due to a Zika virus-driven anamnestic anti-Dengue virus response. The increased specificity provided by homologous antigen quenching is likely to provide a significant improvement in sero-diagnostics and to be of clinical value.

    Published in: PLoS One. 2019;14(8):e0215708

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    Factors predicting the severity of dengue in patients with warning signs in Rio de Janeiro, Brazil (1986–2012)

    By Goncalves BS, Nogueira RMR, Bispo de Filippis AM, Horta MAP

    Since 1981, >12 million cases of dengue have been reported in Brazil. Early prediction of severe dengue with no warning signs is crucial to avoid progression to severe dengue. Here we aimed to identify early markers of dengue severity and characterize dengue infection in patients in Rio de Janeiro.

    Published in: Trans R Soc Trop Med Hyg. 2019;113(11):670-677

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    Follow up of Children with Confirmed Perinatal Zika Virus (ZIKV) Exposure: The First 2 years-experience in the Costa Rican Tertiary Pediatric Hospital

    By H Brenes-Chacón, ML Ávila-Agüero, K Camacho-Badilla, G Naranjo-Zuñiga, A Benavides-Lara, A Soriano-Fallas

    Poster presented at the ID Week, Washington DC, October 2nd – 6th 2019

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    Yellow Fever virus reemergence and spread in southeast Brazil, 2016-2019

    By Giovannetti M, de Mendonca MCL, Fonseca V, et al.

    The recent reemergence of yellow fever virus (YFV) in Brazil has raised serious concerns due to the rapid dissemination of the virus in the southeastern region. To better understand YFV genetic diversity and dynamics during the recent outbreak in southeastern Brazil, we generated 18 complete and nearly complete genomes from the peak of the epidemic curve from nonhuman primates (NHPs) and human infected cases across the Espírito Santo and Rio de Janeiro states.

    Published in: J Virol. 2019;94(1). pii: e01623-19