ZIKA-VT aims to conduct prospective cohort studies in South and Central America and the Caribbean in order to assess:
- 1) Association between ZIKV infection in pregnacy and adverse pregnancy and fetal/infant outcomes
- 2) Risk of vertical transmission of ZIKV by gestational age at different time points during pregnancy and by maternal, infant and viral factors
- 3) Incidence of ZIKV infection in pregnancy, as well as risk factors and clinical presentation.
This WP is lead by the University of the West Indies , with Univerisity College, London co-leading.
The figure below shows the flows of subjects involved in these studies. Pregnant women will be recruited from sites in Jamaica, Haiti, Brazil and Costa Rica.
Specific tasks in this work package include study staff training, enrollment into studies, maternal clinical follow-up, prospective vertical transmission study, laboratory testing and biobanking and statistical analysis.