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WP1 ZIKA-VT

ZIKA-VT aims to conduct prospective cohort studies in South and Central America and the Caribbean in order to assess:

  • 1) Association between ZIKV infection in pregnacy and adverse pregnancy and fetal/infant outcomes
  • 2) Risk of vertical transmission of ZIKV by gestational age at different time points during pregnancy and by maternal, infant and viral factors
  • 3) Incidence of ZIKV infection in pregnancy, as well as risk factors and clinical presentation.

This WP is lead by the University of the West Indies , with Univerisity College, London  co-leading.

The figure below shows the flows of subjects involved in these studies. Pregnant women will be recruited from sites in Jamaica, Haiti, Brazil and Costa Rica.

zika-vt

Specific tasks in this work package include study staff training, enrollment into studies, maternal clinical follow-up, prospective vertical transmission study, laboratory testing and biobanking and statistical analysis.